The signs and symptoms of herpes zoster are usually distinctive enough to make an accurate clinical diagnosis once the rash has appeared. Varicella zoster virus (VZV) laboratory testing information applies to testing and diagnosis of primary VZV infection (varicella) as well as reactivation or latent infection (herpes zoster). Lab Tests Online: Empower Your Health. Understand Your Tests. Also known as: Varicella Zoster Virus; VZV; Herpes Zoster. Formal name: Varicella Zoster Virus Culture; Varicella Zoster Virus by PCR; Varicella Zoster Virus by DFA; Varicella Zoster Virus Antibodies, IgG and IgM.
In select patient populations, however, the presentation of herpes zoster can be atypical and may require additional testing. This is particularly true in immunocompromised patients. Blood work or other testing is usually not necessary. Tests for detecting herpes simplex virus and varicella-zoster virus infections.
Varicella-Zoster Virus and Herpes Simplex Virus DFA with Reflex to Varicella-Zoster Virus Culture and Herpes Simplex Virus Culture 0060283Method: Direct Fluorescent Antibody Stain/Cell Culture. Shingles, also known as zoster, herpes zoster, or zona, is a viral disease characterized by a painful skin rash with blisters involving a limited area. The most popular test detects VZV-specific IgM antibody in blood; this appears only during chickenpox or shingles and not while the virus is dormant. Results from cord blood, neonates, or immunocompromised individuals should be interpreted with caution. Testing for IgM-class antibodies to varicella-zoster virus (VZV) should be limited to patients with a clinically compatible disease. Up to one-third of individuals with primary herpes simplex virus (HSV) infections who have experienced prior VZV infection show a heterotypic antibody response to VZV antigen making a differential diagnosis between VZV and HSV difficult in the absence of clear-cut clinical findings.
Herpes Zoster Workup: Approach Considerations, Laboratory Studies, Other Studies
Yes, there are blood tests for shingles, which is also a herpes virus (herpes zoster, also called varicella-zoster). I’ve had a thyroid test, AIDS test, diabetes test. Ingles -RRB- is a painful, blistering skin rash due to acute infection with the varicella – zoster virus, the virus that causes chickenpox. The varicella-zoster virus (VZV) is a member of the herpes virus family. The virus can potentially cause birth defects or illness in the baby, so doctors often order blood tests to screen for VZV in pregnant women who aren’t immune to the virus. If elevated white blood cells are observed, your doctor may test your blood for antibodies to the herpes zoster virus. Antibodies are proteins that your body makes due to infections and can be detected by laboratory tests. Varicella-zoster virus (VZV) infection causes two clinically distinct forms of disease. Clin Diagn Lab Immunol 2001; 8:909. Use and limitations of varicella-zoster virus-specific serological testing to evaluate breakthrough disease in vaccinees and to screen for susceptibility to varicella. Antibody testing: IgM and IgG antibody, produced by the body in response to infection by the virus, are tested in the blood. This test looks for antibodies in your blood that your body makes against the varicella-zoster virus. It causes a painful rash called shingles, or herpes zoster.
IgM tests may cross-react with several other viruses like the Herpes Zoster that results in chicken pox. However, the IgG antibody blood test can break down the HSV 1 and 2 a little more accurately. Blood tests are available for people who may not have had symptoms or if the signs have already healed. The accurate herpes blood tests detect IgG antibodies. Herpes zoster (shingles) occurs when the virus becomes active again. Blood tests may be done to see if you have become infected with the virus or have had the disease in the past. Diagnosis of Shingles of Herpes Zoster may be made only on the basis of clinical examination of the lesion, symptoms and a past history of chicken pox infection. In addition, routine blood tests may show a rise in the numbers of white blood cells and antibodies or fighter molecules against the chickenpox.
This test differentiates between VZV and HSV viral types. Skin biopsy, taking a piece of skin rash and looking at it under the microscope, is another possible way to diagnose herpes zoster. (I had the blood test, not a swab test, and I’ve never had anything remotely approaching symptoms. Herpes zoster oticus, or Ramsay Hunt syndrome, is a unique variety of viral labyrinthitis. Routine blood tests are not helpful; neither are viral antibody tests.